Biodiesel blends of B20 or less can be operated in any diesel engine with little or no modification to the engine or the fuel system.
The specifications for biodiesel have been established so that it can be used in any diesel engine. Some modifications may be desirable with higher biodiesel concentrations.
Biodiesel has a solvent effect that may release deposits accumulated on tank walls and pipes from previous diesel fuel storage. The release of deposits may clog filters initially and precautions should be taken.
Consult your equipment manufacturer before using higher biodiesel blends, especially in low temperatures.